I have to say I have mixed feelings about this. Civilization V has shaped up to be one of my favorite games. I have sunk many, many hours into that game which, for all the shoddiness of it's AI, has fantastic gameplay. More of that gameplay, in my opinion, isn't a bad thing.
But that said, watching this looks like... more of that gameplay. In fact, it looks remarkably like a reskin of the original game. One might even say a substantial mod.
Yes, it has a revamped tech tree which ought to be interesting. I've only played one other game with a tech web, and it does change things to an extent. But the change isn't that substantial.
The quest system seems like a simple, but nice, addition. Almost seems akin to EUIV's National Missions.
I'm just afraid that this game will come out in October shiny, new, and feeling stale.